West Nile Virus Claims First Colorado Life of 2025; Officials Urge Caution as Cases Rise

Colorado has reported its first West Nile Virus-related death of 2025, involving an adult from Lafayette in Boulder County, according to the Denver Gazette. Health officials warn that more deaths are likely as mosquito activity increases through summer.

So far, nine other cases have been confirmed across eight counties, though none have proven fatal. Historically, Colorado sees an average of 10 to 11 deaths annually from the virus.

Last year, the state recorded just 76 human cases, its lowest total since 2020. That’s a significant drop from 634 cases in 2023, which included 51 deaths—the highest in recent years. On average, Colorado has seen about 323 cases per year since 2003.

While most people infected with West Nile Virus show mild or no symptoms, those aged 60 and older, or with pre-existing health conditions, face a higher risk of serious illness or death. Early signs of severe infection include intense headaches and confusion—symptoms that require immediate medical attention.

With mosquito season in full swing, health officials emphasize prevention. The Colorado Department of Public Health and Environment (CDPHE) recommends the following:

  • Use insect repellent containing DEET, picaridin, IR3535, oil of lemon eucalyptus, or para-menthane-diol.

  • Avoid outdoor activities during peak mosquito hoursdusk and dawn.

  • Wear long-sleeved shirts and pants to reduce skin exposure.

Given Colorado’s outdoor lifestyle and the rising presence of West Nile Virus, taking these precautions is critical for staying safe this summer.

This article has been carefully fact-checked by our editorial team to ensure accuracy and eliminate any misleading information. We are committed to maintaining the highest standards of integrity in our content.

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